NCCN指南已經(jīng)將CPT-11聯(lián)合鉑類列為晚期非小細(xì)胞肺癌一線治療方案。本項(xiàng)研究結(jié)果顯示,CPT-11+DDP治療晚期NSCLC療效確切,用藥劑量患者尚可耐受,對(duì)于CPT-11所導(dǎo)致的骨髓抑制及腹瀉反應(yīng)及早進(jìn)行干預(yù),但對(duì)于晚期復(fù)治及多程治療后患者及KPS評(píng)分<70分患者,如何使用CPT-11值得進(jìn)一步深入研究。
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